Bogdan Mateescu
Dr. Bogdan Mateescu is a leading scientist in RNA biology, currently spearheading a research group at the Brain Research Institute of the University of Zurich (UZH), and contributing as a visiting scientist at the Institute for Chemical and Bioengineering at the ETH Zurich.
Biography
As an active member of the NIH Extracellular RNA Communication Consortium (NIH ERCC, www.exRNA.org) and affiliated with multiple prestigious research groups and programs, Dr. Mateescu's commitment to scientific advancement is evident. His leadership has culminated in over 20 high-impact publications, paralleled by his substantial contributions to funded research projects, amounting to over 4.9 million CHF in the last decade, from prestigious funding agencies such as the Bill and Melinda Gates Foundation, NIH, Novartis Foundation, and Swiss National Scientific Foundation (SNSF).
Bogdan's academic journey began at the École Normale Supérieure de Lyon in France, where he acquired a B.Sc. and a M.Sc. in Molecular and Cellular Biology, further extending his expertise with a M.Sc. in Neurosciences from Sorbonne University, France. He obtained his Ph.D. in Molecular Virology from Sorbonne University and the world-renowned Institut Pasteur (France) working on the mechanism of epigenetic and RNA regulation of HIV-1 provirus.
During his postdoctoral work at Institute Curie, he delved into the role of microRNAs in ovarian cancer, utilizing both mouse models and human clinical samples to advance our understanding of these novel RNA regulators in cancer biology. Transitioning to Switzerland and ETH Zurich as a EU Marie Curie Fellow, Bogdan was at the vanguard of exploring the biogenesis and function of extracellular RNA in animals. His trailblazing efforts in this emerging field garnered him a Principal Investigator position within the NIH Extracellular RNA Communication Consortium (NIH ERCC, www.exRNA.org), allowing him to lead his own research group at the Mansuy lab.
Bogdan's multifaceted scientific background covers a broad range, including virology (Mateescu et al., EMBO report 2004, 2008); cancer research (Mateescu et al., Nature Medicine 2011); the development of cutting edge microfluidics technologies (Holzner & Mateescu et al., Cell report, 2021), and extracellular RNA (Laplante & Stürchler et al., Cell Genomics, 2023). His career is punctuated by innovative research that bridges various domains of RNA science, reflecting a commitment to advancing our knowledge and treatment of complex biological systems and diseases. Bogdan leads a cutting edge research group that pushes the envelope in understanding and utilizing RBPs and cf-RNA for significant medical advancements. Join the group on this journey as they chart unexplored territories of the RNA landscape, translating our discoveries into revolutionary therapies and diagnostic tools for improving patient health.
Mateescu Group
At the Mateescu Group, we're deeply engaged in unraveling the mysteries of RNA biology. Our focus is on the transformative roles of RNA-binding proteins (RBPs) and cell-free RNA (cf-RNA), delving into their crucial impact on cellular stress responses, differentiation, and disease processes.
Our Mission:
We are committed to charting new territories in RNA biology. Our goal is to translate our discoveries into revolutionary RNA therapies and diagnostic tools. We believe in the power of research to enhance patient health and advance scientific understanding, striving to make meaningful contributions that extend beyond the laboratory.
Key areas of interest:
-
RNA-Binding Proteins:
Investigating the intricate roles of RBPs in the life cycle of RNA and cellular functionality. -
Cell-Free RNA:
Exploring cf-RNA's potential as a game-changer in disease monitoring and the creation of cutting-edge RNA therapeutics. -
Innovative Technologies:
Pioneering new methodologies, from CRISPR/Cas9 genome engineering to advanced bioinformatic analyses, to harness the full potential of RNA science.
Join the Mateescu group
Be part of our journey as we explore the uncharted territories of RNA biology, translating our findings into groundbreaking medical advancements. Learn more about our work and Dr. Mateescu's contributions on our group's page or through his publications on Google Scholar.